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Refrigerant guide: all refrigerants, GWP values and safety classes

From legacy CFCs and HCFCs to today's HFCs, low-GWP HFO blends and natural refrigerants: properties, uses and alternatives of 28 refrigerants.

In shortWhen choosing or servicing a refrigerant, three things matter: global warming potential (GWP), safety class (A1, A2L, A3, B2L) and operating pressure. Each of the 28 refrigerants below has its own page with properties, uses, service notes, regulations and alternatives.

All refrigerants at a glance

RefrigerantFamilyGWPSafetyBoiling pointTypical useStatus
R1270Hydrocarbon (natural)2A3−47.6 °CAir-cooled chillersNext generation
R290Hydrocarbon (natural)3A3−42.1 °CAir-to-water monobloc heat pumpsNext generation
R600aHydrocarbon (natural)3A3−11.7 °CDomestic refrigerators and freezersIn common use
R717Natural refrigerant0B2L−33.3 °CCold stores and logistics centresIn common use
R744Natural refrigerant1A1−78.5 °C*Transcritical supermarket booster systemsNext generation
R1234yfHFO4A2L−29.5 °CNew car air conditioningNext generation
R1234zeHFO7A2L−19.0 °CScrew and centrifugal chillersNext generation
R1233zdHCFO1A118.3 °CLow-pressure centrifugal chillersNext generation
R514AHFO/HFC blend2B129.0 °CRetrofit of R123 centrifugal chillers and new low-pressure chillersNext generation
R454CHFO/HFC blend148A2L−46.0 °CCommercial refrigeration and condensing unitsNext generation
R454BHFO/HFC blend466A2L−50.9 °CNew packaged and rooftop unitsNext generation
R513AHFO/HFC blend631A1−29.2 °CScrew and centrifugal chillersIn common use
R448AHFO/HFC blend1,387A1−45.9 °CSupermarket refrigerationIn common use
R449AHFO/HFC blend1,397A1−46.0 °CSupermarket and commercial refrigerationIn common use
R452AHFO/HFC blend2,140A1−47.0 °CTruck and container refrigerationBeing phased down
R32HFC675A2L−51.7 °CNew split and multi-split air conditionersIn common use
R134aHFC1,430A1−26.1 °CScrew and centrifugal chillersBeing phased down
R407CHFC blend1,774A1−43.6 °CPackaged and rooftop unitsBeing phased down
R407FHFC blend1,825A1−46.1 °CSupermarket refrigerationBeing phased down
R410AHFC blend2,088A1−51.4 °CSplit and multi-split air conditionersBeing phased down
R417AHFC blend2,346A1−39.1 °CRetrofit of R22 air conditioners and heat pumpsBeing phased down
R422DHFC blend2,729A1−43.2 °CRetrofit of R22 chillersBeing phased down
R404AHFC blend3,922A1−46.2 °CCold rooms and cold storesBeing phased down
R507AHFC blend3,985A1−46.7 °CCold storesBeing phased down
R123HCFC77B127.8 °CLow-pressure centrifugal chillersBanned / legacy
R22HCFC1,810A1−40.8 °COld split and ducted air conditionersBanned / legacy
R502CFC4,657A1−45.3 °COld cold rooms and blast freezersBanned / legacy
R12CFC10,900A1−29.8 °COld domestic refrigerators and freezersBanned / legacy

GWP values are the IPCC AR4 (100-year) values used in F-gas legislation and are approximate. *R744 sublimes at atmospheric pressure.

Refrigerant families

  • CFC (R12, R502): strongly ozone-depleting, banned.
  • HCFC (R22, R123): ozone-depleting, phased out.
  • HFC and HFC blends (R134a, R32, R410A, R404A, R407C): no ozone impact; high-GWP ones are being restricted.
  • HFO and HFO blends (R1234yf, R1234ze, R454B, R513A, R448A): low or very low GWP, many are A2L.
  • Hydrocarbons (R290, R600a, R1270): natural, very low GWP, highly flammable (A3).
  • Natural refrigerants (R744 CO₂, R717 ammonia): GWP 0–1, need dedicated system design.

GWP, ODP and CO₂ equivalent

GWP shows how much warming 1 kg of a gas causes over 100 years compared with 1 kg of CO₂. Under F-gas rules, leak-check and record-keeping obligations are based on tonnes of CO₂ equivalent: charge (kg) × GWP ÷ 1,000. For example, 3 kg of R410A is about 6.3 t CO₂e, while the same amount of R32 is about 2 t CO₂e.

Safety classes

  • A1: lower toxicity, non-flammable (R410A, R134a, R404A, R744)
  • A2L: lower toxicity, mildly flammable (R32, R454B, R1234yf, R1234ze)
  • A3: lower toxicity, highly flammable (R290, R600a, R1270)
  • B1 / B2L: higher toxicity (R123, R514A / R717)

Regulations in Türkiye

Fluorinated gases are regulated by the Regulation on Fluorinated Greenhouse Gases published in the Official Gazette on 15 October 2024. HFC supply is being phased down, and according to Ministry presentations new single split air conditioners with less than 3 kg of HFC with a GWP of 750 or more are banned from the market from 2027. Always check the current legal text for exact dates and scope.

Refrigerant pages

Our base is in Ankara Etimesgut. We work daily in Ankara and on a project and contract basis across Türkiye. Türkçe sayfa.

Frequently asked questions

Which refrigerant is most common in air conditioners?

Today most new split air conditioners use R32. Units sold over the last two decades mostly use R410A, older ones R22. R290 and R454B are spreading in new products.

Can I put a different refrigerant in my air conditioner?

No. A unit must run on the refrigerant it was designed for; pressures, oil and safety values differ.

Why are blends charged in liquid phase?

In blends such as R404A, R407C and R410A the components boil at different temperatures; vapour charging changes the composition.

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