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Measuring pressures on a R452A refrigeration system

R452A refrigerant: properties, uses and alternatives

R452A replaces R404A mainly in transport refrigeration and low-temperature applications.

In shortR452A replaces R404A mainly in transport refrigeration and low-temperature applications. Its discharge temperature is close to R404A, which makes retrofits easy.

R452A properties

CodeR452A
Chemical name / compositionBlend of R32, R125 and R1234yf
R32 / R125 / R1234yf (11% / 59% / 30%)
FamilyHFO/HFC blend
GWP (AR4, 100 years)2,140
ODP0
Safety class (ISO 817 / ASHRAE 34)A1: lower toxicity, non-flammable
Boiling point (1 atm)−47.0 °C
Temperature glide3.8 K
Charge equal to 5 t CO₂e2.34 kg
StatusBeing phased down

Where is R452A used?

  • Truck and container refrigeration
  • Low-temperature commercial refrigeration

Service and safety notes

  • Zeotropic blend, glide about 3.8 K: always charge in liquid phase; after a large leak, recover and recharge the full system. Use dew point for superheat and bubble point for subcooling.
  • Non-flammable and low toxicity (A1). A large leak in a closed room can still displace oxygen, so gas detection is recommended in small plant rooms.
  • Never charge a system with a refrigerant other than the one on its nameplate; retrofits need manufacturer approval and oil and component checks.
  • Charging, recovery and leak checks must be done and recorded by F-gas certified technicians.

R452A and regulations

Covered by Türkiye's Regulation on Fluorinated Greenhouse Gases (Official Gazette, 15 October 2024). HFC supply is being phased down with quotas, high-GWP gases are restricted earlier, leak-check intervals depend on the CO₂-equivalent charge, and handling requires certified technicians. Always check the current legal text for exact dates and scope.

Alternatives to R452A

  • R448A: HFO/HFC blend, GWP 1,387, A1
  • R449A: HFO/HFC blend, GWP 1,397, A1
  • R744: Natural refrigerant, GWP 1, A1

Compare all refrigerants in our refrigerant guide.

Other refrigerants

Our base is in Ankara Etimesgut. We work daily in Ankara and on a project and contract basis across Türkiye. Türkçe sayfa.

Frequently asked questions

What is the GWP of R452A?

The 100-year global warming potential (AR4) of R452A is about 2,140.

Is R452A flammable?

A1: lower toxicity, non-flammable.

What can replace R452A?

Depending on the application: R448A, R449A, R744. Conversions require manufacturer approval and oil and component checks.

Service for R452A systems

Site survey, measured diagnosis and a written quote. Based in Ankara, working across Türkiye.

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