Authorized Service · TSE Service Competence Certified · ISO 9001 · OHSAuthorized Service · Serving all 81 provinces of TürkiyeServing all of Türkiye0312 261 07 24info@yoimuhendislik.com.tr
Process and refrigeration equipment in an industrial plant

Freeze drying (lyophilization) cooling systems

Maintenance, repair, installation and projects for shelf cooling, ice condensers and cascade refrigeration of pharmaceutical, biotech, food and laboratory freeze dryers.

In shortIn freeze drying the product is frozen and its ice is removed under vacuum by sublimation. The vapour is captured on an ice condenser kept very cold, typically between −50 °C and −85 °C. The refrigeration system cools both the shelves and the condenser, so most units have two-stage or cascade circuits.

Role of refrigeration

  • Freezing: cooling the shelf heat transfer fluid.
  • Primary drying: keeping the condenser cold enough to capture vapour as ice.
  • Secondary drying: controlled shelf heating while the condenser stays cold.
  • Defrost: hot gas or water defrost of the condenser.

Common problems

  • Condenser not reaching temperature (leak, cascade stage failure, dirty condenser)
  • Vacuum not pulling down (vapour reaching the vacuum pump)
  • Shelf temperature drifting (circulation pump, expansion valve, control)
  • Oil return problems at low temperature

In GMP environments every intervention is documented, and qualification work is coordinated with the site quality team.

Maintenance, repair, installation and projects

  • Scheduled maintenance: condenser and evaporator cleaning, compressor and oil checks, pressure and temperature measurements, safety device tests, measured report.
  • Fault diagnosis and repair: not reaching set temperature, slow pull-down, high/low pressure alarms, compressor failure, leaks, control and sensor faults.
  • Installation and projects: load calculation, system and refrigerant selection, compressor and heat exchanger selection, installation, commissioning and documentation.
  • Retrofit and modernisation: conversion to new refrigerants, compressor overhaul, control upgrades, energy efficiency improvements.

We work brand-independent; refrigerant handling is done by F-gas certified technicians.

Our base is in Ankara Etimesgut. We work daily in Ankara and on a project and contract basis across Türkiye. Türkçe sayfa.

Frequently asked questions

Which brands do you service?

We work brand-independent, using the nameplate, circuit diagram and fault records for diagnosis.

Do you work outside Ankara?

Yes. We are based in Ankara and work across Türkiye on a project, contract and scheduled service basis.

Do you also design and install new systems?

Yes. We calculate loads, select the system and refrigerant, install and commission.

Get a quote for your freeze drying system

Site survey, measured diagnosis and a written quote. Based in Ankara, working across Türkiye.

Contact us

Get a quote, we reply the same day

Briefly describe your equipment and needs and one of our engineers will call you. One contact for breakdowns, maintenance, contracts and new equipment.

Authorized ServiceTSE Service Competence CertificateSince 2009

Quick quote form

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For a detailed request, use our quote form.